Skin Care

Chronic Wound Care

Nutritional Supplements

News

 

 

Science

Bio-Cartilage / anti-inflammatory and immune system responses

  1. Prudden JF, Balassa, LL. The biological activity of bovine cartilage preparations, Semin Arthritis Rheum 3: 287-321, 1974.

  2. Romano CF, Lipton A, Harvey HA, Simmonds MA, Romano PJ.  A Phase II study of Cartix-S in solid tumors.  J Biol Response Mod 4: 585-9, 1985.

  3. Prudden JF.  The treatment of human cancer with agents prepared from bovine cartilage. 
    J Biol Response Mod 4: 551-84, 1985.

  4. Lescarden, Inc.  (internal corporate document).  A Summary of Toxicity Studies Conducted with Catrix and Catrix-S [confidential].

  5. Moses Ma, Sidhalter J, Langer R. Identification of an inhibitor of neovascularization from cartilage.  Science 248: 1408-10, 1990.

  6. Langer R, Brem H, Falterman K, Klein M, Folkman J.  Isolation of a cartilage factor that inhibits tumor neovascularization. Science 193: 70-2, 1976.

  7. Langer R, Conn H, Vacanti J, Haudenschild c, Folkman J.  Control of tumor growth in animals by infusion of an angiongenisis inhibitor.  Proc Natl Acad Sci USA 77: 4331-5, 1980.

  8. Rosen J, Sherman WT, Prudden JF, Thorbecke GJ.  Immunoregulatory Effects of Catrix.  
    J Biol Response Mod 7: 498-512, 1988.

  9. Rosen J, Sherman WT, Farrington GL, Thorbecke GJ.  Chondroitin sulfates used as adjuvant for antibody formation and as mitogens for B cells.  J Biol Response Mod 6: 355- 66, 1987.

  10. Zhengyi JZ, Lee CSY, Lider O,  Weinder HL.  Suppression of adjuvant arthritis in Lewis rats by oral administration of Type II collagen.  J Immunol 145: 2489-93, 1990.

  11. Trentham DE, Dynesius-Trentham RA, Orav EJ, et al.  Effect of oral administration of Type II collagen rheumatoid arthritis.  Science: 261: 1727-30, 1993.

  12. Burkhardt D, Gnosh P.  Laboratory evaluation of antiarthritic drugs as potential chondroprotective agents.  Semin Arthritis Rheum 17: 3-33, 1987.

  13. Rejholec V.  Long-term studies of antiosteoarthritic drugs:  An Assessment.  Semin Arthritis Rheum 17: 35-53, 1987.

  14. Puccio, C., Mittelman A. Treatmant of Metastatic Renal Cell Carcinoma with Catrix. Reprinted Report To American Society of Clinical Oncology, May, 1994,

  15. Morrision LM. Absorption, distribution, metabolism and excretion of acid        mucoploysaccharides administered to animals and patients.  In: Coronary Heart Disease and the Mucopolysaccharides.  C C Thomas, Springfield (IL), 1974, pages 109-27.

  16. Morrison LM, Enrick NL.  Coronary heart disease:  Reduction of death rate by chondroitin sulfate A. Angiology 24: 269-86, 1973.

  17. Pollastri M, Saccocci M, Corsi C.  Controlled clinical trial on the therapeutic efficacy and safety of a sulfomucopolysaccharide preparation in the treatment of peripheral atherosclerotic disease.  Curr Ther Res 50: 133-38, 1991